Semax
Cognitive & Nootropic
Not Approved
CognitiveNeuroprotectionNootropicBDNF
Semax is a synthetic heptapeptide analog of the ACTH(4-10) fragment, developed in Russia in the 1980s by the Institute of Molecular Genetics. It is approved as a pharmaceutical drug in Russia for cognitive impairment, is…
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PE-22-28
Cognitive & Neurological
Not Approved
CognitiveNootropicAntidepressantTREK-1MyelinationPreclinical
PE-22-28 is a synthetic fragment of spadin (a naturally occurring peptide derived from the NTSR3/sortilin propeptide) that antagonizes TREK-1, a two-pore domain potassium channel (K2P channel) that regulates neuronal exc…
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Stack Compatibility & Key Differences
Both are active research compounds. See individual pages for full protocol data.
Frequently Asked Questions
What is the difference between Semax and PE-22-28?
Semax: Semax is a synthetic heptapeptide analog of the ACTH(4-10) fragment, developed in Russia in the 1980s by the Institute of Molecular Genetics. It is approved as a pharmaceutical drug in Russia for cognitive impairment, is… PE-22-28: PE-22-28 is a synthetic fragment of spadin (a naturally occurring peptide derived from the NTSR3/sortilin propeptide) that antagonizes TREK-1, a two-pore domain potassium channel (K2P channel) that regulates neuronal exc…
Can you stack Semax and PE-22-28?
Both are active research compounds. See individual pages for full protocol data.
Which has a longer half-life, Semax or PE-22-28?
Semax half-life: ~minutes (plasma); CNS effects 24h+. PE-22-28 half-life: - .