Cognitive
Semax Dosing & Reconstitution Calculator
Nootropic heptapeptide supporting BDNF, focus, memory, and mood.
TL;DR - Semax is a cognitive peptide with a typical starting dose of 500 µg. For a 10 mg vial, add 2 mL bacteriostatic water to yield 5000 µg/mL.
500 µg
Start Dose
10 mg
Vial
2 mL
BAC Water
5000
µg/mL
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Frequently Asked
How do I reconstitute Semax?
Add 2 mL of bacteriostatic water to a 10 mg vial, injecting slowly down the inside wall. Swirl gently; never shake. This yields a concentration of 5000 µg/mL.
What is the recommended dose of Semax?
A typical research dose is 500 µg. Consult the ASCEND calculator for your specific vial concentration and draw volume.
How many doses are in a Semax vial?
A 10 mg vial reconstituted with 2 mL BAC water yields approximately 20 doses at 500 µg each.
How many IU is 500 µg of Semax on a syringe?
With a 10 mg vial reconstituted in 2 mL bacteriostatic water, the concentration is 5000 µg/mL. For a 500 µg dose: Volume = 500 µg ÷ 5000 µg/mL = 0.1 mL. Draw to the 10 line on a 100-unit insulin syringe. You can adjust these values in the ASCEND calculator for any vial size.
What does a Semax dosage calculator do?
A Semax dosage calculator converts your vial size and BAC water volume into an exact syringe draw in IU. Enter your vial strength (10 mg), reconstitution volume (2 mL), and target dose to get the precise line to draw on an insulin syringe.
What is the Semax reconstitution calculator formula?
Draw volume (mL) = Dose (µg) divided by Concentration (µg/mL). For a 10 mg vial with 2 mL BAC water: concentration = 5000 µg/mL. For a 500 µg dose, the ASCEND calculator gives the exact IU line on your syringe instantly.
Peptide Intelligence
What is the mechanism of Semax?
Semax is a synthetic heptapeptide analog of ACTH(4-7). It enhances BDNF and NGF production, increases dopaminergic and serotonergic activity, and modulates the melanocortin system. Primary research applications are cognitive enhancement and neuroprotection.
What is the half-life of Semax?
Semax has a very short plasma half-life of approximately 30–90 minutes due to rapid enzymatic breakdown. Intranasal administration provides more direct CNS delivery. Subcutaneous administration requires more frequent dosing than intranasal routes.
How does Semax compare to N-Acetyl Semax?
N-Acetyl Semax has greater CNS penetration and longer duration of action than standard Semax due to its acetyl modification. Standard Semax is most commonly used intranasally in Russia for stroke recovery. N-Acetyl versions are preferred by many researchers for longer-lasting effects.
Also Explore
Research Guides
Bacteriostatic Water Guide
What it is & why it matters for reconstitution
How Much BAC Water for Semax?
10 mg vial reconstitution recipe + concentration table
Semax on Insulin Syringe
500 µg draw on 30u / 50u / 100u syringes
Semax + Cerebrolysin Stack
Neurotrophic peptide complex + BDNF upregulation
Semax + Dihexa Stack
Synaptogenesis + BDNF + dopaminergic tone
Insulin Syringe Guide
Choosing the right gauge & volume for your draw
Multi-Lab Verification Standard
How ASCEND ensures dosing accuracy
Primary Sources
BDNF Upregulation (Neuropeptides 2010)
Data last reviewed 2026-06-03 · Methodology →
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