Acetylated Semax variant with enhanced bioavailability and longer duration.
TL;DR — N-Acetyl Semax is a cognitive peptide with a typical starting dose of 300 µg. For a 5 mg vial, add 2 mL bacteriostatic water to yield 2500 µg/mL.
Add 2 mL of bacteriostatic water to a 5 mg vial, injecting slowly down the inside wall. Swirl gently; never shake. This yields a concentration of 2500 µg/mL.
What is the recommended dose of N-Acetyl Semax?
A typical research dose is 300 µg. Consult the ASCEND calculator for your specific vial concentration and draw volume.
How many doses are in a N-Acetyl Semax vial?
A 5 mg vial reconstituted with 2 mL BAC water yields approximately 16 doses at 300 µg each.
Peptide Intelligence
What does the N-Acetyl modification do to Semax?
N-Acetylation at the N-terminus increases Semax's resistance to aminopeptidases, extending its half-life and improving CNS penetration. The modification also changes its receptor binding profile slightly, potentially enhancing selectivity for key neurotrophin targets.
What are common administration routes for N-Acetyl Semax?
N-Acetyl Semax is used intranasally (most common for direct CNS delivery), subcutaneously, and in some protocols intramuscularly. Intranasal administration bypasses first-pass metabolism and leverages olfactory nerve pathways for rapid CNS uptake.
What cognitive benefits is N-Acetyl Semax researched for?
Research areas include improved working memory, focus, and information processing speed. It is studied for neuroprotection post-stroke, anxiety reduction, and BDNF-mediated depression models. Effects on dopamine transporter expression have been documented in animal studies.