Add 2 mL of bacteriostatic water to a 10 mg vial, injecting slowly down the inside wall. Swirl gently; never shake. This yields a concentration of 5000 µg/mL.
What is the recommended dose of P21?
A typical research dose is 500 µg. Consult the ASCEND calculator for your specific vial concentration and draw volume.
How many doses are in a P21 vial?
A 10 mg vial reconstituted with 2 mL BAC water yields approximately 20 doses at 500 µg each.
Peptide Intelligence
What is the mechanism of P21 peptide?
P21 is derived from Ciliary Neurotrophic Factor (CNTF) and acts as a CNTF mimetic, activating JAK-STAT3 signaling to promote neurogenesis, neural progenitor cell proliferation, and synaptic plasticity. It increases hippocampal neurogenesis in rodent models.
What cognitive effects has P21 shown in research?
Rodent studies show P21 improves spatial memory, pattern separation, and reversal learning. It shows promise in models of cognitive aging and early neurodegeneration, with neurogenesis increases measurable after 4–6 weeks of administration.
What are the storage requirements for P21?
Store P21 as lyophilized powder at -20°C for long-term stability. After reconstitution, refrigerate at 2–8°C and use within 14–21 days. Avoid repeated freeze-thaw cycles. Protect from light during storage and handling.