⚖ Head-to-Head · Systemic Repair vs Collagen

TB-500 vs GHK-Cu

Mechanism, half-life, dosing & research status compared side-by-side.

TB-500
Healing & Recovery
Not Approved
HealingRecoveryCardiacAnti-inflammatory
TB-500 is a synthetic fragment of Thymosin Beta-4 (Tβ4), a naturally occurring 43-amino acid peptide found in virtually all human and animal cells. It is particularly concentrated in platelets and wound fluid, where it p…
Full TB-500 profile →
GHK-Cu
Skin & Connective Tissue
Not Approved (Injectable)
SkinHealingAnti-agingConnective Tissue
GHK-Cu (Glycine-Histidine-Lysine Copper Complex) is a naturally occurring tripeptide with high affinity for copper(II) ions, found in human plasma, saliva, and urine. Plasma levels decline significantly with age - from ~…
Full GHK-Cu profile →
Technical Specs Comparison
MetricTB-500GHK-Cu
Research Status Extensively Studied Extensively Studied
Molecular Weight 4,963 Da 340.4 Da (free), ~402 Da (complex)
Half-Life ~5 days ~30 min (plasma)
Peak Time ~2–4 hours ~20 min
Typical Dose 2.5–5 mg 1–2 mg
Frequency 2–3× per week Once daily
Route Subcutaneous Subcutaneous / Topical
Amino Acids 43 3
WADA Status Prohibited Not Listed
FDA Status Not Approved Not Approved (Injectable)
Stack Compatibility & Key Differences
Both are active research compounds. See individual pages for full protocol data.
PK Plotter · Visualize plasma levels over time
Plot TB-500 → Plot GHK-Cu →
Frequently Asked Questions
What is the difference between TB-500 and GHK-Cu?
TB-500: TB-500 is a synthetic fragment of Thymosin Beta-4 (Tβ4), a naturally occurring 43-amino acid peptide found in virtually all human and animal cells. It is particularly concentrated in platelets and wound fluid, where it p… GHK-Cu: GHK-Cu (Glycine-Histidine-Lysine Copper Complex) is a naturally occurring tripeptide with high affinity for copper(II) ions, found in human plasma, saliva, and urine. Plasma levels decline significantly with age - from ~…
Can you stack TB-500 and GHK-Cu?
Both are active research compounds. See individual pages for full protocol data.
Which has a longer half-life, TB-500 or GHK-Cu?
TB-500 half-life: ~5 days. GHK-Cu half-life: ~30 min (plasma).
Verified Scientific Data
All specifications on this page are sourced from peer-reviewed literature and primary research. Half-life values, dosing ranges, and mechanism data are cross-referenced against published studies. Last audited 2026-06-24.
Peer-reviewed sources Audit timestamp: 2026-06-24 Data version: ASCEND Wiki 2026
Data sourced from ASCEND Wiki · TB-500 profile · GHK-Cu profile · All comparisons
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