Immune-modulating thymic peptide enhancing T-cell function and pathogen defense.
TL;DR — Thymosin Alpha-1 is a longevity peptide with a typical starting dose of 1.5 mg. For a 10 mg vial, add 2 mL bacteriostatic water to yield 5 mg/mL.
Add 2 mL of bacteriostatic water to a 10 mg vial, injecting slowly down the inside wall. Swirl gently; never shake. This yields a concentration of 5 mg/mL.
What is the recommended dose of Thymosin Alpha-1?
A typical research dose is 1.5 mg. Consult the ASCEND calculator for your specific vial concentration and draw volume.
How many doses are in a Thymosin Alpha-1 vial?
A 10 mg vial reconstituted with 2 mL BAC water yields approximately 6 doses at 1.5 mg each.
Peptide Intelligence
What is Thymosin Alpha-1 and how does it modulate immunity?
Thymosin Alpha-1 (Ta1) is a 28-amino acid peptide naturally produced by the thymus. It matures and activates T-cells, dendritic cells, and NK cells by signaling through Toll-like receptors 2 and 9. It enhances adaptive immunity while modulating inflammatory overactivation.
What is the half-life of Thymosin Alpha-1?
Thymosin Alpha-1 has a short half-life of approximately 2 hours after subcutaneous injection. Standard clinical dosing (as Zadaxin) is 1.6 mg twice weekly. The immunological effects on T-cell maturation persist well beyond plasma clearance of the peptide.
What is Thymosin Alpha-1 approved for in some countries?
Thymosin Alpha-1 (Zadaxin) is approved in over 35 countries for treatment of hepatitis B and C, certain immunodeficiencies, and as an adjuvant in cancer immunotherapy. It is used clinically in Asia and South America. It remains investigational in the US and EU.