Longevity
AICAR Dosing & Reconstitution Calculator
AMPK activator mimicking exercise benefits at the cellular level.
TL;DR - AICAR is a longevity peptide with a typical starting dose of 50 mg. For a 50 mg vial, add 1 mL bacteriostatic water to yield 50 mg/mL.
50 mg
Start Dose
50 mg
Vial
1 mL
BAC Water
50
mg/mL
Compare Similar
Frequently Asked
How do I reconstitute AICAR?
Add 1 mL of bacteriostatic water to a 50 mg vial, injecting slowly down the inside wall. Swirl gently; never shake. This yields a concentration of 50 mg/mL.
What is the recommended dose of AICAR?
A typical research dose is 50 mg. Consult the ASCEND calculator for your specific vial concentration and draw volume.
How many doses are in a AICAR vial?
A 50 mg vial reconstituted with 1 mL BAC water yields approximately 1 doses at 50 mg each.
How many IU is 50 mg of AICAR on a syringe?
With a 50 mg vial reconstituted in 1 mL bacteriostatic water, the concentration is 50 mg/mL. For a 50 mg dose: Volume = 50 mg ÷ 50 mg/mL = 1 mL. Draw to the 100 line on a 100-unit insulin syringe. You can adjust these values in the ASCEND calculator for any vial size.
What does a AICAR dosage calculator do?
A AICAR dosage calculator converts your vial size and BAC water volume into an exact syringe draw in IU. Enter your vial strength (50 mg), reconstitution volume (1 mL), and target dose to get the precise line to draw on an insulin syringe.
What is the AICAR reconstitution calculator formula?
Draw volume (mL) = Dose (mg) divided by Concentration (mg/mL). For a 50 mg vial with 1 mL BAC water: concentration = 50 mg/mL. For a 50 mg dose, the ASCEND calculator gives the exact IU line on your syringe instantly.
Peptide Intelligence
What is AICAR and how does it activate AMPK?
AICAR is a cell-permeable nucleotide analog that is phosphorylated intracellularly to ZMP, an AMP mimetic. ZMP allosterically activates AMP-activated protein kinase (AMPK), the master cellular energy sensor, mimicking the metabolic effects of caloric restriction and exercise.
What metabolic effects does AICAR produce?
AICAR increases glucose uptake, fatty acid oxidation, mitochondrial biogenesis, and GLUT4 translocation via AMPK. In rodent studies it improves endurance capacity without exercise. It also activates SIRT1, PGC-1a, and other longevity-associated pathways.
Is AICAR a peptide?
Technically, AICAR is a nucleotide analog rather than a traditional peptide. It is commonly included in peptide research compound databases due to its overlapping research context and subcutaneous administration route. It shares mechanism overlap with MOTS-C through shared AMPK activation pathways.
Also Explore
Research Guides
Bacteriostatic Water Guide
What it is & why it matters for reconstitution
How Much BAC Water for AICAR?
50 mg vial reconstitution recipe + concentration table
AICAR on Insulin Syringe
50 mg draw on 30u / 50u / 100u syringes
Insulin Syringe Guide
Choosing the right gauge & volume for your draw
Multi-Lab Verification Standard
How ASCEND ensures dosing accuracy
Cite This Calculator