Recovery & Repair
ARA-290 Dosing & Reconstitution Calculator
Non-hematopoietic EPO-derived peptide for neuropathic pain and tissue protection.
TL;DR - ARA-290 is a recovery & repair peptide with a typical starting dose of 4 mg. For a 16 mg vial, add 1 mL bacteriostatic water to yield 16 mg/mL.
4 mg
Start Dose
16 mg
Vial
1 mL
BAC Water
16
mg/mL
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Frequently Asked
How do I reconstitute ARA-290?
Add 1 mL of bacteriostatic water to a 16 mg vial, injecting slowly down the inside wall. Swirl gently; never shake. This yields a concentration of 16 mg/mL.
What is the recommended dose of ARA-290?
A typical research dose is 4 mg. Consult the ASCEND calculator for your specific vial concentration and draw volume.
How many doses are in a ARA-290 vial?
A 16 mg vial reconstituted with 1 mL BAC water yields approximately 4 doses at 4 mg each.
How many IU is 4 mg of ARA-290 on a syringe?
With a 16 mg vial reconstituted in 1 mL bacteriostatic water, the concentration is 16 mg/mL. For a 4 mg dose: Volume = 4 mg ÷ 16 mg/mL = 0.25 mL. Draw to the 25 line on a 100-unit insulin syringe. You can adjust these values in the ASCEND calculator for any vial size.
What does a ARA-290 dosage calculator do?
A ARA-290 dosage calculator converts your vial size and BAC water volume into an exact syringe draw in IU. Enter your vial strength (16 mg), reconstitution volume (1 mL), and target dose to get the precise line to draw on an insulin syringe.
What is the ARA-290 reconstitution calculator formula?
Draw volume (mL) = Dose (mg) divided by Concentration (mg/mL). For a 16 mg vial with 1 mL BAC water: concentration = 16 mg/mL. For a 4 mg dose, the ASCEND calculator gives the exact IU line on your syringe instantly.
Peptide Intelligence
What is ARA-290 and how does it work?
ARA-290 is an 11-amino acid peptide derived from erythropoietin (EPO) that selectively activates the innate repair receptor (IRR), a heterodimer of the EPO receptor and beta common receptor. Unlike EPO, it has no hematopoietic activity and does not affect red blood cell production.
What is the half-life of ARA-290?
ARA-290 has a short half-life of approximately 2–4 hours, necessitating daily subcutaneous injections in research protocols. It does not bind the classical EPO receptor homodimer, carrying no thromboembolic risk associated with EPO itself.
What neuropathy applications is ARA-290 researched for?
ARA-290 has been studied for small fiber neuropathy, diabetic peripheral neuropathy, and sarcoidosis-associated neuropathy. Clinical trials have shown reduction in neuropathic pain scores and improvement in corneal nerve fiber density over treatment periods.
Also Explore
Research Guides
Bacteriostatic Water Guide
What it is & why it matters for reconstitution
How Much BAC Water for ARA-290?
16 mg vial reconstitution recipe + concentration table
ARA-290 on Insulin Syringe
4 mg draw on 30u / 50u / 100u syringes
Insulin Syringe Guide
Choosing the right gauge & volume for your draw
Multi-Lab Verification Standard
How ASCEND ensures dosing accuracy
Primary Sources
Innate Repair Receptor (PNAS 2010)
ClinicalTrials NCT01184274
Data last reviewed 2026-06-03 · Methodology →
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