Add 1 mL of bacteriostatic water to a 5 mg vial, injecting slowly down the inside wall. Swirl gently; never shake. This yields a concentration of 5000 µg/mL.
What is the recommended dose of Cortagen?
A typical research dose is 200 µg. Consult the ASCEND calculator for your specific vial concentration and draw volume.
How many doses are in a Cortagen vial?
A 5 mg vial reconstituted with 1 mL BAC water yields approximately 25 doses at 200 µg each.
Peptide Intelligence
What is Cortagen and what does it target?
Cortagen (Ala-Glu-Asp-Pro) is a tetrapeptide bioregulator developed by the Russian Institute of Bioregulation to support cerebral cortex function. It is researched for neuroprotection, cognitive restoration in aging, and recovery from ischemic neurological events.
What is the typical Cortagen research protocol?
Cortagen is typically administered at 100–200 mcg per dose via subcutaneous injection for 10-day courses. Like other bioregulator peptides, it is cycled 2–4 times per year. It is sometimes combined with Pinealon or Epithalon in neurological aging protocols.
How does Cortagen compare to Semax for cognitive applications?
Cortagen is a bioregulator peptide targeting gene expression normalization in aging cortical tissue, while Semax acutely modulates BDNF, dopaminergic, and serotonergic tone. Their mechanisms are distinct; some researchers use both in different phases of a cognitive enhancement protocol.