Longevity
Cortagen Dosing & Reconstitution Calculator
Bioregulator peptide supporting cerebral cortex function.
TL;DR - Cortagen is a longevity peptide with a typical starting dose of 200 µg. For a 5 mg vial, add 1 mL bacteriostatic water to yield 5000 µg/mL.
200 µg
Start Dose
5 mg
Vial
1 mL
BAC Water
5000
µg/mL
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Frequently Asked
How do I reconstitute Cortagen?
Add 1 mL of bacteriostatic water to a 5 mg vial, injecting slowly down the inside wall. Swirl gently; never shake. This yields a concentration of 5000 µg/mL.
What is the recommended dose of Cortagen?
A typical research dose is 200 µg. Consult the ASCEND calculator for your specific vial concentration and draw volume.
How many doses are in a Cortagen vial?
A 5 mg vial reconstituted with 1 mL BAC water yields approximately 25 doses at 200 µg each.
How many IU is 200 µg of Cortagen on a syringe?
With a 5 mg vial reconstituted in 1 mL bacteriostatic water, the concentration is 5000 µg/mL. For a 200 µg dose: Volume = 200 µg ÷ 5000 µg/mL = 0.04 mL. Draw to the 4 line on a 100-unit insulin syringe. You can adjust these values in the ASCEND calculator for any vial size.
What does a Cortagen dosage calculator do?
A Cortagen dosage calculator converts your vial size and BAC water volume into an exact syringe draw in IU. Enter your vial strength (5 mg), reconstitution volume (1 mL), and target dose to get the precise line to draw on an insulin syringe.
What is the Cortagen reconstitution calculator formula?
Draw volume (mL) = Dose (µg) divided by Concentration (µg/mL). For a 5 mg vial with 1 mL BAC water: concentration = 5000 µg/mL. For a 200 µg dose, the ASCEND calculator gives the exact IU line on your syringe instantly.
Peptide Intelligence
What is Cortagen and what does it target?
Cortagen (Ala-Glu-Asp-Pro) is a tetrapeptide bioregulator developed by the Russian Institute of Bioregulation to support cerebral cortex function. It is researched for neuroprotection, cognitive restoration in aging, and recovery from ischemic neurological events.
What is the typical Cortagen research protocol?
Cortagen is typically administered at 100–200 mcg per dose via subcutaneous injection for 10-day courses. Like other bioregulator peptides, it is cycled 2–4 times per year. It is sometimes combined with Pinealon or Epithalon in neurological aging protocols.
How does Cortagen compare to Semax for cognitive applications?
Cortagen is a bioregulator peptide targeting gene expression normalization in aging cortical tissue, while Semax acutely modulates BDNF, dopaminergic, and serotonergic tone. Their mechanisms are distinct; some researchers use both in different phases of a cognitive enhancement protocol.
Also Explore
Research Guides
Bacteriostatic Water Guide
What it is & why it matters for reconstitution
How Much BAC Water for Cortagen?
5 mg vial reconstitution recipe + concentration table
Cortagen on Insulin Syringe
200 µg draw on 30u / 50u / 100u syringes
Insulin Syringe Guide
Choosing the right gauge & volume for your draw
Multi-Lab Verification Standard
How ASCEND ensures dosing accuracy
Data last reviewed 2026-06-03 · Methodology →
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