Longevity
Humanin Dosing & Reconstitution Calculator
Mitochondrial peptide with cytoprotective and anti-apoptotic properties.
TL;DR - Humanin is a longevity peptide with a typical starting dose of 2 mg. For a 5 mg vial, add 2 mL bacteriostatic water to yield 2.5 mg/mL.
2 mg
Start Dose
5 mg
Vial
2 mL
BAC Water
2.5
mg/mL
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Frequently Asked
How do I reconstitute Humanin?
Add 2 mL of bacteriostatic water to a 5 mg vial, injecting slowly down the inside wall. Swirl gently; never shake. This yields a concentration of 2.5 mg/mL.
What is the recommended dose of Humanin?
A typical research dose is 2 mg. Consult the ASCEND calculator for your specific vial concentration and draw volume.
How many doses are in a Humanin vial?
A 5 mg vial reconstituted with 2 mL BAC water yields approximately 2 doses at 2 mg each.
How many IU is 2 mg of Humanin on a syringe?
With a 5 mg vial reconstituted in 2 mL bacteriostatic water, the concentration is 2.5 mg/mL. For a 2 mg dose: Volume = 2 mg ÷ 2.5 mg/mL = 0.8 mL. Draw to the 80 line on a 100-unit insulin syringe. You can adjust these values in the ASCEND calculator for any vial size.
What does a Humanin dosage calculator do?
A Humanin dosage calculator converts your vial size and BAC water volume into an exact syringe draw in IU. Enter your vial strength (5 mg), reconstitution volume (2 mL), and target dose to get the precise line to draw on an insulin syringe.
What is the Humanin reconstitution calculator formula?
Draw volume (mL) = Dose (mg) divided by Concentration (mg/mL). For a 5 mg vial with 2 mL BAC water: concentration = 2.5 mg/mL. For a 2 mg dose, the ASCEND calculator gives the exact IU line on your syringe instantly.
Peptide Intelligence
What is Humanin and where does it originate?
Humanin is a 21-amino acid peptide encoded within the 16S rRNA gene of the mitochondrial genome, making it a mitochondria-derived peptide similar to MOTS-C. Its circulating levels decline with age and correlate inversely with insulin resistance and neurodegeneration.
What are the primary cytoprotective mechanisms of Humanin?
Humanin acts via a trimeric cytokine receptor complex and a formyl peptide receptor. It inhibits mitochondrial apoptosis pathways, protects neurons against amyloid-beta toxicity, improves insulin sensitivity, and reduces vascular inflammation.
What is the half-life of Humanin?
Humanin has a short plasma half-life of approximately 30–60 minutes, necessitating daily subcutaneous injection. Humanin-S14G (HNG) is a modified analog with approximately 1000-fold greater potency, often used at lower doses in research protocols.
Also Explore
Research Guides
Bacteriostatic Water Guide
What it is & why it matters for reconstitution
How Much BAC Water for Humanin?
5 mg vial reconstitution recipe + concentration table
Humanin on Insulin Syringe
2 mg draw on 30u / 50u / 100u syringes
Humanin + MOTS-C Stack
Mitochondrial-derived peptide stack
Insulin Syringe Guide
Choosing the right gauge & volume for your draw
Multi-Lab Verification Standard
How ASCEND ensures dosing accuracy
Cite This Calculator