Long-acting insulin-like growth factor for muscle growth and recovery.
TL;DR — IGF-1 LR3 is a growth hormone peptide with a typical starting dose of 40 µg. For a 1 mg vial, add 1 mL bacteriostatic water to yield 1000 µg/mL.
Add 1 mL of bacteriostatic water to a 1 mg vial, injecting slowly down the inside wall. Swirl gently; never shake. This yields a concentration of 1000 µg/mL.
What is the recommended dose of IGF-1 LR3?
A typical research dose is 40 µg. Consult the ASCEND calculator for your specific vial concentration and draw volume.
How many doses are in a IGF-1 LR3 vial?
A 1 mg vial reconstituted with 1 mL BAC water yields approximately 25 doses at 40 µg each.
Peptide Intelligence
How does IGF-1 LR3 differ from native IGF-1?
IGF-1 LR3 has a 13-amino acid extension at the N-terminus and an Arg3 substitution that reduces IGF-binding protein (IGFBP) affinity. This prolongs its half-life from ~10 minutes (native IGF-1) to approximately 20–30 hours, significantly increasing bioavailability.
What is the half-life of IGF-1 LR3?
IGF-1 LR3 has a half-life of approximately 20–30 hours compared to native IGF-1's ~10-minute half-life. This extended duration results from reduced IGFBP binding, allowing more free active peptide in circulation throughout the day.
What are the main considerations for IGF-1 LR3 injection sites?
Research protocols use subcutaneous or intramuscular injection. Intramuscular injection near target muscle groups is used in hypertrophy protocols, though evidence for site-specific effects versus systemic activity remains limited.