Recovery & Repair
LL-37 Dosing & Reconstitution Calculator
Antimicrobial cathelicidin peptide supporting immune defense and wound healing.
TL;DR - LL-37 is a recovery & repair peptide with a typical starting dose of 100 µg. For a 5 mg vial, add 2 mL bacteriostatic water to yield 2500 µg/mL.
100 µg
Start Dose
5 mg
Vial
2 mL
BAC Water
2500
µg/mL
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Frequently Asked
How do I reconstitute LL-37?
Add 2 mL of bacteriostatic water to a 5 mg vial, injecting slowly down the inside wall. Swirl gently; never shake. This yields a concentration of 2500 µg/mL.
What is the recommended dose of LL-37?
A typical research dose is 100 µg. Consult the ASCEND calculator for your specific vial concentration and draw volume.
How many doses are in a LL-37 vial?
A 5 mg vial reconstituted with 2 mL BAC water yields approximately 50 doses at 100 µg each.
How many IU is 100 µg of LL-37 on a syringe?
With a 5 mg vial reconstituted in 2 mL bacteriostatic water, the concentration is 2500 µg/mL. For a 100 µg dose: Volume = 100 µg ÷ 2500 µg/mL = 0.04 mL. Draw to the 4 line on a 100-unit insulin syringe. You can adjust these values in the ASCEND calculator for any vial size.
What does a LL-37 dosage calculator do?
A LL-37 dosage calculator converts your vial size and BAC water volume into an exact syringe draw in IU. Enter your vial strength (5 mg), reconstitution volume (2 mL), and target dose to get the precise line to draw on an insulin syringe.
What is the LL-37 reconstitution calculator formula?
Draw volume (mL) = Dose (µg) divided by Concentration (µg/mL). For a 5 mg vial with 2 mL BAC water: concentration = 2500 µg/mL. For a 100 µg dose, the ASCEND calculator gives the exact IU line on your syringe instantly.
Peptide Intelligence
What is the mechanism of LL-37?
LL-37 is a cathelicidin antimicrobial peptide that disrupts bacterial membranes, modulates TLR-signaling to reduce inflammatory overactivation, stimulates wound healing via EGFR and FPRL1 receptors, and promotes angiogenesis.
What is the half-life of LL-37?
LL-37 has a very short plasma half-life (minutes to a couple of hours) due to rapid proteolytic degradation. Research protocols frequently use subcutaneous injection, often daily or every other day, tailored to the indication.
Is LL-37 involved in immune modulation beyond antimicrobial action?
LL-37 is a potent immunomodulator. It reduces excessive pro-inflammatory signaling via TLR2/4 while promoting adaptive immunity. In autoimmune and wound contexts, its dual anti-inflammatory and pro-healing profile makes it an active research subject.
Also Explore
Research Guides
Bacteriostatic Water Guide
What it is & why it matters for reconstitution
How Much BAC Water for LL-37?
5 mg vial reconstitution recipe + concentration table
LL-37 on Insulin Syringe
100 µg draw on 30u / 50u / 100u syringes
Insulin Syringe Guide
Choosing the right gauge & volume for your draw
Multi-Lab Verification Standard
How ASCEND ensures dosing accuracy
Primary Sources
Cathelicidin Review (Cell Mol Life Sci 2006)
Data last reviewed 2026-06-03 · Methodology →
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