PEGylated Mechano Growth Factor for localized muscle repair and hypertrophy.
TL;DR — PEG-MGF is a growth hormone peptide with a typical starting dose of 200 µg. For a 2 mg vial, add 2 mL bacteriostatic water to yield 1000 µg/mL.
Add 2 mL of bacteriostatic water to a 2 mg vial, injecting slowly down the inside wall. Swirl gently; never shake. This yields a concentration of 1000 µg/mL.
What is the recommended dose of PEG-MGF?
A typical research dose is 200 µg. Consult the ASCEND calculator for your specific vial concentration and draw volume.
How many doses are in a PEG-MGF vial?
A 2 mg vial reconstituted with 2 mL BAC water yields approximately 10 doses at 200 µg each.
Peptide Intelligence
What is PEGylated MGF and why is it PEGylated?
PEG-MGF is the IGF-1Ec splice variant with polyethylene glycol attached to extend its half-life. Native MGF has a half-life of only a few minutes; PEGylation extends this to several days, enabling once or twice-weekly dosing for muscle repair research.
When is the optimal timing for PEG-MGF administration?
PEG-MGF is typically administered following resistance exercise or injury, as MGF is naturally upregulated in mechanically stressed muscle. Post-workout administration within 30–60 minutes is standard in muscle satellite cell activation protocols.
How does PEG-MGF differ from IGF-1 LR3?
PEG-MGF primarily activates muscle satellite cells (myogenic precursor cells) for local muscle repair, while IGF-1 LR3 has broader systemic anabolic effects. PEG-MGF is considered more tissue-specific; some researchers use both in sequence for maximal muscle recovery protocols.