Metabolic & Weight

Cagrilintide Dosing & Reconstitution Calculator

Long-acting amylin analog that promotes satiety and supports weight loss.

TL;DR — Cagrilintide is a metabolic & weight peptide with a typical starting dose of 0.3 mg. For a 10 mg vial, add 3 mL bacteriostatic water to yield 3.3 mg/mL.
0.3 mg
Start Dose
10 mg
Vial
3 mL
BAC Water
3.3
mg/mL
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Frequently Asked
How do I reconstitute Cagrilintide?
Add 3 mL of bacteriostatic water to a 10 mg vial, injecting slowly down the inside wall. Swirl gently; never shake. This yields a concentration of 3.3 mg/mL.
What is the recommended dose of Cagrilintide?
A typical research dose is 0.3 mg. Consult the ASCEND calculator for your specific vial concentration and draw volume.
How many doses are in a Cagrilintide vial?
A 10 mg vial reconstituted with 3 mL BAC water yields approximately 33 doses at 0.3 mg each.
Peptide Intelligence
What is the half-life of Cagrilintide?
Cagrilintide has a half-life of approximately 7 days, supporting once-weekly dosing. As a long-acting amylin analog, it works through different receptors than GLP-1 agonists, making it complementary in combination protocols.
How does Cagrilintide complement Semaglutide?
Cagrilintide acts on amylin/calcitonin receptors, slowing gastric emptying and reducing glucagon, while Semaglutide targets GLP-1 receptors. Phase 3 CagriSema trials showed additive weight loss exceeding either agent alone.
What are storage requirements for Cagrilintide?
Store lyophilized Cagrilintide at 2–8°C. After reconstitution with bacteriostatic water, refrigerate and use within 28 days. Allow to reach room temperature before injection to reduce injection site discomfort.
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Primary Sources
CagriSema Phase 1b (Lancet 2021) ClinicalTrials NCT05066854
Data last reviewed 2026-04-19 · Methodology →
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