Metabolic & Weight
Cagrilintide Dosing & Reconstitution Calculator
Long-acting amylin analog promoting satiety. Combined with semaglutide (CagriSema), REDEFINE-1 showed ~22.7% weight loss.
TL;DR - Cagrilintide is a metabolic & weight peptide with a typical starting dose of 0.3 mg. For a 10 mg vial, add 3 mL bacteriostatic water to yield 3.3 mg/mL.
0.3 mg
Start Dose
10 mg
Vial
3 mL
BAC Water
3.3
mg/mL
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Frequently Asked
How do I reconstitute Cagrilintide?
Add 3 mL of bacteriostatic water to a 10 mg vial, injecting slowly down the inside wall. Swirl gently; never shake. This yields a concentration of 3.3 mg/mL.
What is the recommended dose of Cagrilintide?
A typical research dose is 0.3 mg. Consult the ASCEND calculator for your specific vial concentration and draw volume.
How many doses are in a Cagrilintide vial?
A 10 mg vial reconstituted with 3 mL BAC water yields approximately 33 doses at 0.3 mg each.
How many IU is 0.3 mg of Cagrilintide on a syringe?
With a 10 mg vial reconstituted in 3 mL bacteriostatic water, the concentration is 3.3 mg/mL. For a 0.3 mg dose: Volume = 0.3 mg ÷ 3.3 mg/mL = 0.09 mL. Draw to the 9 line on a 100-unit insulin syringe. You can adjust these values in the ASCEND calculator for any vial size.
What does a Cagrilintide dosage calculator do?
A Cagrilintide dosage calculator converts your vial size and BAC water volume into an exact syringe draw in IU. Enter your vial strength (10 mg), reconstitution volume (3 mL), and target dose to get the precise line to draw on an insulin syringe.
What is the Cagrilintide reconstitution calculator formula?
Draw volume (mL) = Dose (mg) divided by Concentration (mg/mL). For a 10 mg vial with 3 mL BAC water: concentration = 3.3 mg/mL. For a 0.3 mg dose, the ASCEND calculator gives the exact IU line on your syringe instantly.
Peptide Intelligence
What is the half-life of Cagrilintide?
Cagrilintide has a half-life of approximately 7 days, supporting once-weekly dosing. As a long-acting amylin analog, it works through different receptors than GLP-1 agonists, making it complementary in combination protocols.
How does Cagrilintide complement Semaglutide?
Cagrilintide acts on amylin/calcitonin receptors, slowing gastric emptying and reducing glucagon, while Semaglutide targets GLP-1 receptors. Phase 3 CagriSema trials showed additive weight loss exceeding either agent alone.
What are storage requirements for Cagrilintide?
Store lyophilized Cagrilintide at 2–8°C. After reconstitution with bacteriostatic water, refrigerate and use within 28 days. Allow to reach room temperature before injection to reduce injection site discomfort.
Also Explore
Research Guides
Bacteriostatic Water Guide
What it is & why it matters for reconstitution
How Much BAC Water for Cagrilintide?
10 mg vial reconstitution recipe + concentration table
Cagrilintide on Insulin Syringe
0.3 mg draw on 30u / 50u / 100u syringes
Cagrilintide + Retatrutide Stack
Triple agonist + amylin analog
Cagrilintide + Semaglutide Stack
GLP-1 agonist + amylin analog (CagriSema)
Insulin Syringe Guide
Choosing the right gauge & volume for your draw
Multi-Lab Verification Standard
How ASCEND ensures dosing accuracy
Primary Sources
CagriSema Phase 1b (Lancet 2021)
ClinicalTrials NCT05066854
Data last reviewed 2026-06-03 · Methodology →
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