Add 2 mL of bacteriostatic water to a 5 mg vial, injecting slowly down the inside wall. Swirl gently; never shake. This yields a concentration of 2500 µg/mL.
What is the recommended dose of DSIP?
A typical research dose is 100 µg. Consult the ASCEND calculator for your specific vial concentration and draw volume.
How many doses are in a DSIP vial?
A 5 mg vial reconstituted with 2 mL BAC water yields approximately 50 doses at 100 µg each.
Peptide Intelligence
What is the mechanism of DSIP?
DSIP modulates sleep architecture by reducing delta (slow-wave) sleep latency and normalizing circadian rhythm disruptions. It acts on opioid receptors, modulates cortisol and ACTH secretion, and has antioxidant properties. It is also researched for pain modulation and stress resilience.
What is the half-life of DSIP?
DSIP has a short plasma half-life of approximately 8 minutes, though its effects on sleep architecture persist for hours after administration. This dissociation suggests receptor-mediated downstream signaling rather than direct ongoing receptor occupancy.
What is the typical research protocol for DSIP?
DSIP is typically administered in the late evening via subcutaneous injection, 100–200 mcg, 1–2 hours before intended sleep time. Some protocols use 5-day cycles followed by rest periods. It is being studied for insomnia, opiate withdrawal, and stress-related sleep dysfunction.