Sexual Health

Oxytocin Dosing & Reconstitution Calculator

Neuropeptide hormone promoting bonding, stress relief, and social cognition.

TL;DR — Oxytocin is a sexual health peptide with a typical starting dose of 10 µg. For a 5 mg vial, add 1 mL bacteriostatic water to yield 5000 µg/mL.
10 µg
Start Dose
5 mg
Vial
1 mL
BAC Water
5000
µg/mL
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Frequently Asked
How do I reconstitute Oxytocin?
Add 1 mL of bacteriostatic water to a 5 mg vial, injecting slowly down the inside wall. Swirl gently; never shake. This yields a concentration of 5000 µg/mL.
What is the recommended dose of Oxytocin?
A typical research dose is 10 µg. Consult the ASCEND calculator for your specific vial concentration and draw volume.
How many doses are in a Oxytocin vial?
A 5 mg vial reconstituted with 1 mL BAC water yields approximately 500 doses at 10 µg each.
Peptide Intelligence
What is the half-life of Oxytocin?
Intranasal Oxytocin has a plasma half-life of approximately 3 minutes for the peripheral fraction. Central effects are believed to persist longer via direct nose-to-brain delivery through olfactory/trigeminal pathways, bypassing the blood-brain barrier. Research often uses intranasal routes for behavioral studies.
What receptors does Oxytocin act on beyond social bonding?
Oxytocin acts on OXTR receptors expressed in the brain, uterus, mammary glands, heart, and immune cells. Beyond bonding, it modulates pain perception, anxiety, HPA axis stress responses, cardiovascular function, and gut motility.
What behavioral and psychiatric effects is Oxytocin researched for?
Active research areas include social anxiety disorder, autism spectrum disorder, PTSD, postpartum depression, and addiction. Meta-analyses show modest but consistent pro-social and anxiolytic effects. Nasal Oxytocin research has produced mixed results, partly due to delivery reliability challenges.
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Primary Sources
Bonding & Stress Review (Nat Rev Neurosci 2008)
Data last reviewed 2026-04-19 · Methodology →
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