Once-weekly GLP-1 agonist for glycemic control in type 2 diabetes.
TL;DR — Dulaglutide is a metabolic & weight peptide with a typical starting dose of 1.5 mg. For a 1.5 mg vial, add 0.5 mL bacteriostatic water to yield 3 mg/mL.
Add 0.5 mL of bacteriostatic water to a 1.5 mg vial, injecting slowly down the inside wall. Swirl gently; never shake. This yields a concentration of 3 mg/mL.
What is the recommended dose of Dulaglutide?
A typical research dose is 1.5 mg. Consult the ASCEND calculator for your specific vial concentration and draw volume.
How many doses are in a Dulaglutide vial?
A 1.5 mg vial reconstituted with 0.5 mL BAC water yields approximately 1 doses at 1.5 mg each.
Peptide Intelligence
What is the half-life of Dulaglutide?
Dulaglutide has a half-life of approximately 5 days, enabling once-weekly dosing. Its GLP-1 analog is fused to a modified IgG4-Fc antibody fragment, extending its half-life through FcRn-mediated recycling.
How is Dulaglutide different from other GLP-1 agonists?
Dulaglutide is a fusion protein (GLP-1 analog fused to IgG4-Fc), whereas Semaglutide and Liraglutide use fatty acid conjugation. The fusion protein approach gives Dulaglutide a different immunogenicity and injection site tolerability profile.
What are storage requirements for Dulaglutide?
Dulaglutide solutions require refrigeration at 2–8°C. Research-grade lyophilized preparations should similarly be stored cold and protected from freezing. Discard any solution that appears cloudy or discolored.