Metabolic & Weight

Mazdutide Dosing & Reconstitution Calculator

GLP-1/glucagon dual agonist being developed for obesity treatment.

TL;DR — Mazdutide is a metabolic & weight peptide with a typical starting dose of 3 mg. For a 6 mg vial, add 1 mL bacteriostatic water to yield 6 mg/mL.
3 mg
Start Dose
6 mg
Vial
1 mL
BAC Water
6
mg/mL
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Frequently Asked
How do I reconstitute Mazdutide?
Add 1 mL of bacteriostatic water to a 6 mg vial, injecting slowly down the inside wall. Swirl gently; never shake. This yields a concentration of 6 mg/mL.
What is the recommended dose of Mazdutide?
A typical research dose is 3 mg. Consult the ASCEND calculator for your specific vial concentration and draw volume.
How many doses are in a Mazdutide vial?
A 6 mg vial reconstituted with 1 mL BAC water yields approximately 2 doses at 3 mg each.
Peptide Intelligence
What is the mechanism of Mazdutide?
Mazdutide is a dual GLP-1/glucagon receptor agonist designed for once-weekly subcutaneous administration. The glucagon component enhances energy expenditure and hepatic fat clearance beyond what GLP-1 alone achieves.
What clinical outcomes has Mazdutide shown?
Phase 2 and 3 trials in Chinese populations showed significant weight loss (up to 14–18% at higher doses over 24 weeks) and HbA1c reduction. Mazdutide is in advanced clinical development for obesity and type 2 diabetes.
What are storage guidelines for Mazdutide?
Store lyophilized Mazdutide at 2–8°C protected from light. Reconstituted solution should be refrigerated and used within 28 days. Do not freeze reconstituted solution. Allow to warm to room temperature before subcutaneous injection.
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Primary Sources
Phase 2 China (Lancet Diabetes 2023)
Data last reviewed 2026-04-19 · Methodology →
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